Fenacetin
Fenacetin CAS:62-44-2
Fenacetin Chemical Properties
MF: C10H13NO2
MW: 179,22
Bod tání: 133-136 ° C (svítí)
Bod varu: 132 ° C / 4 mmHg
Hustota: 1,1248 (hrubý odhad)
Fenacetin Specification:
Test% â ‰ ¥ 99,0
organický chlorid% â ‰ 0,02
p-Fenetidin - světle červená € 4 #
Snadná směs uhlíku - 4 # € 6 #
Ztráta sušením v% - 0,5
Teplota tání: 134-137 ° C
Zbytky zapalování% â ‰ ¤ 0,1
Fenacetin Introduction:
Fenacetin is a non-opioid analgesic without anti-inflammatory properties, inhibits COX-3 activity.Target: COXFenacetin is a pain-relieving and fever-reducing drug,
Fenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy. the clinical and laboratory data were compatible with“phenacetin nephritis”as described in Europe and Australia and recently in the United States and Canada.
This report evaluates the findings in the 23 cases and cautions against the use of phenacetin, particularly in patients with impaired renal function [1]. Fenacetin has been linked to renal papillary necrosis in human beings [2, 3].
Fenacetin Application:
Antipyretické analgetikum, používané k léčbě horečky, bolesti hlavy, neuralgie atd
